Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Active skin cooling in conjunction with laser dermatologic surgery.

J S Nelson1, B Majaron, K M Kelly

  • 1Beckman Laser Institute and Medical Clinic, Department of Surgery, University of California, Irvine 92612, USA.

Seminars in Cutaneous Medicine and Surgery
|January 10, 2001
PubMed
Summary

Selective skin cooling during laser treatment protects the epidermis from thermal injury. This technique allows for effective targeting of chromophores, improving outcomes for dermatologic conditions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Title: Obesogenic microbial signatures and the development of obesity in childhood acute lymphoblastic leukemia.

Leukemia research·2023
Same author

From FOS fusions to somatic mutations in the MAPK pathway, heterogeneous genetic abnormalities cause distinct pathophysiology among subsets of epithelioid haemangiomas.

The British journal of dermatology·2022
Same author

Development of a core outcome domain set for clinical research on capillary malformations (the COSCAM project).

Journal of the European Academy of Dermatology and Venereology : JEADV·2021
Same author

Understanding the relationship between type 2 diabetes and depression: lessons from genetically informative study designs.

Diabetic medicine : a journal of the British Diabetic Association·2020
Same author

The Association of Airflow Obstruction with Occupational Exposures in a Sample of Rural Adults in Iowa.

COPD·2020
Same author

Accuracy of Intercepting Moving Tactile Targets.

Perception·2019

Area of Science:

  • Dermatology
  • Biomedical Engineering
  • Optical Engineering

Background:

  • Laser treatment aims to damage target chromophores while sparing normal skin.
  • Epidermal injury threshold is often close to therapeutic laser dosages, limiting treatment efficacy.
  • Selective skin cooling is a key strategy to mitigate epidermal damage.

Purpose of the Study:

  • To review active skin cooling techniques used in laser dermatologic surgery.
  • To analyze the advantages and disadvantages of these cooling methods.
  • To discuss their application in treating specific dermatoses.

Main Methods:

  • Active cooling via cryogen spray.
  • Active cooling using cold sapphire contact handpieces.
  • Spatially selective epidermal cooling to low temperatures.

Related Experiment Videos

Main Results:

  • Cooling prevents epidermal temperature from exceeding thermal injury thresholds.
  • Rapid, selective cooling is achieved without impacting target chromophore temperature pre-pulse.
  • Cooling is integral to modern laser dermatologic surgery.

Conclusions:

  • Active skin cooling is a critical component of safe and effective laser dermatologic surgery.
  • Various cooling techniques offer distinct benefits and drawbacks for different dermatoses.
  • Further understanding and application of cooling methods can optimize laser therapy outcomes.