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Oxidative phosphorylation in the skeletal muscles of rabbits during dinithrophenol hyperthermia
Bulletin of Experimental Biology and Medicine
|January 1, 1975
Abstract:
After intramuscular injection of 2,4-dinitrophenol (DNP) into rabbits in doses of 10,15, 25, and 30 mg/kg the degree of elevation of the body temperature, the phosphorylation in skeletal muscle homogenates were found o increase with the dose. In the course of dinitrophenol hyperthermia (following injection of 25 mg/kg DNP) the changes in body temperature and oxygen consumption of the animals followed a parallel course with the changes in the level of oxidative phosphorylation in the skeletal muscles.