Echocardiographic evaluation of cardiac functions and left ventricular mass in children with malnutrition

B Ocal1, S Unal, P Zorlu

  • 1Department of Pediatric Cardiology, Dr Sami Ulus Children's Hospital, Ankara, Turkey. burhan.ocal@isbank.net.tr

Insights

Children with protein energy malnutrition (PEM) show reduced left ventricular mass (LV Mass) and cardiac output, proportional to their smaller body size. However, their heart

Area of Science:

  • Pediatric Cardiology
  • Nutritional Science
  • Echocardiography

Background:

  • Protein energy malnutrition (PEM) affects multiple organ systems, including the cardiovascular system.
  • Assessing cardiac structure and function in pediatric malnutrition is crucial for understanding its impact.

Purpose of the Study:

  • To evaluate left ventricular mass (LV Mass) and systolic/diastolic functions in children with PEM.
  • To compare cardiac parameters between children with PEM and healthy controls.

Main Methods:

  • Doppler echocardiography was used to study 30 children with PEM (aged 2 months-2 years) and 17 healthy controls.
  • Participants were categorized based on malnutrition type: kwashiorkor, marasmic-kwashiorkor, and marasmus.

Main Results:

  • Children with PEM had significantly lower mean LV Mass compared to controls (P < 0.05).
  • LV Mass, septal, and posterior wall thickness were reduced proportionally to body size in PEM, with the most significant reductions in the kwashiorkor group.
  • Cardiac output was reduced in proportion to body size in PEM patients; however, cardiac index remained comparable to controls.
  • Left ventricular systolic and diastolic functions were not significantly different between groups.

Conclusions:

  • In children with PEM, LV Mass and cardiac output decrease proportionally with body size.
  • Despite reduced cardiac dimensions, left ventricular systolic and diastolic functions are preserved in malnourished children.
Abstract

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