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Peritoneal dialysis in diabetic patients
1Department of Nephrology, Medical School, Democritus University of Thrace, Alexandroupolis, Greece. ploumis@hol.gr
Summary
Diabetes mellitus is the leading cause of end-stage renal disease (ESRD). This review compares outcomes for diabetic patients undergoing peritoneal dialysis (PD) versus hemodialysis (HD), finding similar survival rates between the two. Continuous ambulatory peritoneal dialysis (CAPD) showed lower survival.
Area of Science:
- Nephrology
- Diabetology
- Renal Replacement Therapy
Background:
- Diabetes mellitus is the fastest-growing cause of end-stage renal disease (ESRD) globally.
- ESRD caused by diabetes increased significantly in the US, Canada, and Europe between 1984 and 1997.
- Continuous ambulatory peritoneal dialysis (CAPD) is often favored for diabetic ESRD, but long-term data is limited.
Purpose of the Study:
- To review literature and clinical experience with diabetic patients undergoing peritoneal dialysis (PD).
- To compare clinical outcomes of diabetic patients undergoing PD versus hemodialysis (HD).
Main Methods:
- Literature review of studies comparing clinical outcomes in diabetic patients undergoing different renal replacement therapies.
- Analysis of clinical outcomes in diabetic patients undergoing PD and HD.
Main Results:
- Diabetic patients undergoing PD and HD likely have similar survival rates.
- Diabetic patients undergoing CAPD demonstrate lower survival and technique success rates compared to non-diabetic patients.
- Limited follow-up data exists for diabetic dialysis patients beyond 5 years due to comorbidities.
Conclusions:
- Diabetic patients undergoing PD and HD show comparable survival.
- CAPD is associated with poorer outcomes in diabetic ESRD patients compared to non-diabetics.
- Further research is needed on long-term outcomes for diabetic patients on PD and HD.