Recurrent endogenous candidal endophthalmitis in a premature infant

Area of Science:

• Ophthalmology
• Neonatology
• Mycology

Background:

• Endogenous Candida endophthalmitis in low-birth-weight infants typically presents as retinochoroiditis.
• Systemic antifungal agents are the standard treatment for this condition.

Observation:

• A case of Candida endophthalmitis recurred 4 months after completing systemic antifungal therapy.

Findings:

• The recurrent infection primarily involved the iris and lens, deviating from the usual retinochoroidal pattern.
• Diagnosis and treatment of the recurrent endophthalmitis necessitated a vitrectomy procedure.

Implications:

• This case highlights the potential for atypical presentations and recurrence of Candida endophthalmitis in infants.
• Ophthalmologists and neonatologists should consider the possibility of recurrent or atypical Candida eye infections, even after initial treatment.
• Vitrectomy may be a crucial intervention for diagnosing and managing recurrent or anteriorly located Candida endophthalmitis.