Morphometrical and mathematical analysis of the ageing changes of the muscle-connective-tissue-relation in smooth...

The rate of the process of ageing studied in this work as well as of other ageing processes observed by us constantly decreases with increasing age. By an adaptation of exponential functions to series of measurements it is possible to estimate the theoretically possible end stage of histological ageing processes for extremely long lifetimes. The histological biomorphosis is much slower in female persons during their generative phase than in males. Results of planimetric measurements made on sections suggest that, so far as the shift in muscle-connective tissue relation in favour of the connective tissue is concerned, primary significance should be attached to muscular atrophy, while the connective-tissue proliferation may be considered to the secondary in this respect.