Related Experiment Video
Updated: Jul 21, 2026

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
Published on: August 13, 2019
Treatment of endodontic perforations by guided tissue regeneration
1Department of Restorative Dentistry, University of California at San Francisco, San Francisco, CA 94143-0758, USA.
Abstract:
Case reports of mandibular molars with iatrogenic perforations are presented. Such perforations have been treated with internal amalgam repair or by surgical intervention. However, the potential exists for tissue migration and pocket formation. The use of guided tissue regeneration as a barrier for apical migration is beneficial in surgical treatment of perforations. Follow-up examination of perforated teeth treated with resorbable barriers showed successful repair. Results obtained with this technique offer the possibility of a successful repair for an otherwise hopeless complication of endodontic therapy.

