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Published on: May 9, 2022
Using the PerioChip in treating adult periodontitis: an interim report
A Stabholz1, L Shapira, D Mahler
1Department of Community Dentistry, Hebrew University, Hadassah Faculty of Dental Medicine, Jerusalem, Israel.
Summary
The PerioChip, a controlled-release chlorhexidine chip, effectively manages adult periodontitis long-term. Adjunctive use with routine care significantly reduces pocket depth for up to two years.
Area of Science:
- Periodontology
- Pharmacology
- Clinical Dentistry
Background:
- The adjunctive use of subgingival controlled-release chlorhexidine (PerioChip) has demonstrated efficacy in managing periodontitis for up to 9 months.
- Existing data supports its role in reducing pocket probing depth and improving periodontal health markers.
Purpose of the Study:
- To evaluate the long-term (2-year) effectiveness of the PerioChip as an adjunctive therapy for adult periodontitis.
- To assess the sustained impact of PerioChip on periodontal parameters in a real-world clinical setting.
Main Methods:
- A 2-year trial involving 836 adult periodontitis patients from private dental offices.
- Initial definitive therapy followed by PerioChip placement in pockets ≥5 mm deep.
- Routine periodontal maintenance therapy with quarterly PerioChip placement in persistent pockets ≥5 mm deep.
Main Results:
- A continuous mean pocket probing depth reduction of 1.26 ± 0.77 mm over 2 years.
- Significant reduction observed primarily in the first 9-12 months, with continued but less marked reduction thereafter.
- At 2 years, 60% of patients showed ≥2 mm reduction in at least two pockets; only 10% had no improvement or increased pocket depth.
Conclusions:
- Adjunctive PerioChip use is a clinically effective long-term management strategy for adult periodontitis.
- The treatment provides sustained benefits in reducing pocket probing depth when used with routine periodontal maintenance.

