[Fibronectin as a diagnostic marker in several determined neurological diseases]

To determinate if fibronectin in CSF can be a useful parameter in the diagnosis of some neurologic illnesses.

We have studied 30 patients, subdivided in four groups, depending on the type of neurologic illness. We have chosen as control a 10-patient group, which came to the Emergency Service and were diagnosed as a suspicious of neurologic illness, but after this it was discarded. In the whole group we practiced a lumbar puncture, with cytology, systematic, biochemistry, cultures, immunoglobulins determination and fibronectin quantification by ELISA.

We want to emphasize the increase in fibronectin levels in CSF in both the patients with bacterial meningitis and the multiple sclerosis groups, when it's compared with the control group.

For this, the determination of fibronectin levels in CSF might be a useful parameter in the diagnosis of some neurologic illnesses.