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Updated: Jul 28, 2026

Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin
Published on: May 6, 2018
[A case report. Hypotensive reaction caused by albumin infusion]
M Eriksson1, B Nilsson, J Modig
1Anestesi- och intensivvårdskliniken, Akademiska sjukhuset, Uppsala.
Abstract:
Hypotensive reactions during surgical procedures cause diagnostic problems in establishing whether the hypotension is due to blood loss or pharmaceuticals or other causes. A case of hypotension probably due to an albumin infusion is described. Bradykinin effects are probably the cause of many hypotensive reactions. Angiotensin-converting enzyme (ACE) inhibitors reduce degradation of bradykinin and thus increase the risk of hypotensive reactions. When possible, doctors should consider withholding ACE inhibitors 24 hours before surgical procedures likely to require albumin transfusions.
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