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[Extramedullary plasmocytoma. Report of 5 cases]
M Zabaleta1, F J García Cano, J A Preciado
1Hospital San Millán, Logroño, La Rioja.
Anales Otorrinolaringologicos Ibero-Americanos
|March 27, 2001
Summary
Extramedullary plasmacytoma, rare plasma cell tumors, often affect the head and neck. Surgical treatment with radiation therapy showed promising results in a small patient group, preventing multiple myeloma progression.
Area of Science:
- Oncology
- Pathology
Background:
- Extramedullary plasmacytoma (EMP) represents 1-2% of plasma cell neoplasms.
- Predominantly occurs in the head and neck region, originating in the submucosa of the upper airways.
- More prevalent in males during their sixth to seventh decades.
Observation:
- This study reports on five cases of EMP: three females and two males.
- One patient initially diagnosed with nasal EMP later developed a tibial epiphysis plasmacytoma.
- All patients underwent surgical treatment, with four receiving complementary radiotherapy.
Findings:
- No patients in this cohort progressed to multiple myeloma following treatment.
- Surgical intervention combined with radiotherapy appears effective for localized EMP.
- Long-term follow-up is crucial due to the potential for delayed transformation.
Implications:
- Highlights the efficacy of combined surgical and radiological treatment for localized EMP.
- Emphasizes the importance of vigilant long-term monitoring for potential multiple myeloma development.
- Suggests a potential role for this treatment approach in managing localized EMP, warranting further investigation.