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Updated: Aug 13, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
[Evidence-based medicine in the further development of health care systems. Comments on a current discussion]
1Medizinischer Dienst der Spitzenverbände der Krankenkassen e.V. (MDS), Essen. j.windeler@mds-ev.de
Abstract:
The concept of evidence-based medicine is applicable also in the field of guiding health care systems to overcome deficits in adequate patient care. EbM has already been used in this field and has passed first tests of its practical application. There are some obstacles against the future esteem of EbM. These include some misunderstanding concerning the concept itself, missing routine where external evidence has to be put into practice, and some general resistance. Details are presented and an adequate usage of EbM is argued for.
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