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A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection
Published on: March 8, 2017
Deep body temperature from aural canal with servo-controlled heating to outer ear
Abstract:
A portable battery-powered device was used to measure temperature in the external aural canal by a thermistor while keeping the temperature of the outer ear, monitored by a second thermistor at the same level by servo-controlled heating. Aural canal temperature then always stabilized within 0.35 degrees C of esophageal in moving air at between 18 and 45 degrees C. It often did so in colder air, but stabilization was slow even after brief exposure to the cold air. Aural temperature then paralleled esophageal within 0.35 degrees C during rapid changes in deep body temperature while rectal temperature was seriously depressed in cold air. These conclusions were based on 30 experiments on 11 male and 7 female subjects.
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Thermosensation
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Step 1: Begin by practicing good hand hygiene to prevent the transmission of microorganisms.
Step 2: Turn on the thermometer and wait until the ready sign appears on the screen to ensure accurate measurement.
Step 3: Slide the probe cover in place to prevent cross-contamination.
Step 4: Instruct the patient to tilt their head to the side for comfort and check for cerumen...
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Step 1: Perform hand hygiene and don a fresh pair of gloves to prevent cross-infection and ensure patient safety.
Step 2: Explain the procedure to the patient to establish trust. Clear communication establishes trust with the patient, ensures they understand what to expect, promotes cooperation, and enhances comfort during the procedure.
Step 3: Assess the patient's forehead...
Anatomy of the Ear

