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Interventions for the treatment of twin-twin transfusion syndrome
D Roberts1, J P Neilson, A M Weindling
1Department of Obstetrics and Gynaecology, Liverpool Women's Hospital NHS Trust, Crown Street, Liverpool, Merseyside, UK, L8 7SS. dkaur@liverpool.ac.uk
Background:
Twin-twin transfusion syndrome, a condition affecting monochorionic twin pregnancies, is associated with a high risk of perinatal mortality and morbidity. A number of treatments have been introduced to treat the condition but it is unclear which intervention improves maternal and fetal outcome.
Objectives:
The objective of this review was to evaluate the impact of treatment modalities in twin-twin transfusion syndrome.
Search Strategy:
We searched The Cochrane Pregnancy and Childbirth Trials Register and Cochrane Controlled Trials Register. We also searched conference proceedings and made personal contact with experts active in the area of the review. Date of last search: August 2000.
Selection Criteria:
Randomised and quasi-randomised studies of amnioreduction versus laser coagulation, septostomy versus laser coagulation or septostomy versus amnioreduction.
Data Collection And Analysis:
Eligibility was assessed by one reviewer. Study authors were contacted for additional information.
Main Results:
No studies were included.
Reviewer'S Conclusions:
There is no current evidence from randomised trials to influence practice. Three ongoing randomised studies have been identified.