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The Y chromosome and its role in testis differentiation and spermatogenesis
1Department of Obstetrics & Gynecology, University of Wisconsin and Promega Corp., Madison, Wisconsin, USA.
Seminars in Reproductive Medicine
|April 13, 2001
Abstract:
The Y chromosome contains genes and gene families that play critical roles in the processes of testis determination and testis differentiation. Great strides have been made toward defining the genetic pathways associated with the determination of gender. The data are summarized and discussed and clinical ramifications are considered.