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Correlation between family history of hypertension and haemostatic disorders
A Trifiletti1, R Scamardi, M Cincotta
1Department of Internal Medicine, University of Messina, Via Monsignor D'Arrigo, 23-98121 Messina, Italy. atrifiletti@tin.it
Background:
The aim of this study was to evaluate whether a family history of hypertension is associated with haemostatic disorders.
Methods:
In 38 normotensive subjects with a family history of hypertension (relatives) and in 46 sex, age and body mass index matched controls with no family history of hypertension, tissue-type plasminogen activator (t-PA), plasminogen activator-inhibitor (PAI-1), D-dimer (DD) and prothrombin fragment 1+2 (F1+2) were evaluated.
Results:
The t-PA and PAI-1 observed values were significantly higher than the values detected in the controls.
Conclusions:
These data seem to suggest a correlation between family history of hypertension and haemostatic disorders.