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Isolation of Intact Eyeball to Obtain Integral Ocular Surface Tissue for Histological Examination and Immunohistochemistry
Published on: October 20, 2019
[A clinicopathological analysis of keratoacanthoma in eye]
1Zongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China.
Purpose:
To discuss clinic and histopathologic features of keratoacanthoma. The diagnosis and differential diagnosis were discussed.
Methods:
The authors analyze clinical characteristics of keratoacanthoma which is testified by hisopathology. Clinically, the tumors developed rapidly. They appeared as a dome or nodule with a central keratin filled crater and elevated rolled margins.
Results:
Histologically, they had a cup-differentiated squamous opithalium surrounding a central mass of keratin. The base was rather uniform. The lesions may extend into underlying stroma even orbicularis muscle.
Conclusion:
Keratoacanthoma is a specialized variant of pseudocarcinomatous hyperplasia. It has clinic and histopathologic characteristics and differs from other tumors.
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