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Excitation-contraction uncoupling: major role in contraction-induced muscle injury
G L Warren1, C P Ingalls, D A Lowe
1Department of Physical Therapy, Georgia State University, Atlanta, Georgia, USA. phtglw@langate.gsu.edu
Exercise and Sport Sciences Reviews
|May 8, 2001
Abstract:
The mechanisms that account for the strength loss after contraction-induced muscle injury remain controversial. We present data showing that (1) most of the early strength loss results from a failure of excitation-contraction coupling and (2) a slow loss of contractile protein in the days after injury prolongs the recovery time.