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Related Experiment Videos

Commercial availability of a house dust mite patch test.

C M Mowad1, C K Anderson

  • 1Department of Dermatology, Geisinger Medical Center, Danville, PA, USA.

American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society
|May 31, 2001
PubMed
Summary

A standardized patch test allergen for house dust mites is now available. This new tool aids in investigating the role of dust mite allergens in atopic dermatitis and skin conditions.

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Area of Science:

  • Allergen immunotherapy
  • Contact dermatitis research
  • Dermatology and immunology

Background:

  • House dust mites are implicated in asthma and allergic rhinitis.
  • Their role in atopic dermatitis and skin disease is debated due to testing limitations.
  • Current testing methods like radioallergosorbent tests (RASTs) and prick testing have limitations.

Purpose of the Study:

  • To introduce a standardized house dust mite allergen preparation for patch testing.
  • To provide a better tool for investigating house dust mite as a contactant in skin disease.

Main Methods:

  • Chemotechnique Diagnostics offers a standardized dust mite allergen in petrolatum.
  • The preparation, Dermatophagoides mix, contains D. pteronyssinus and D. farinae in 20% and 30% concentrations.

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Main Results:

  • A standardized patch test allergen for house dust mites is now available.
  • This standardized allergen facilitates research into the role of dust mites in skin conditions.

Conclusions:

  • The availability of standardized patch test allergens improves the investigation of contact allergens.
  • This advancement offers a more reliable method to study the house dust mite's role in atopic dermatitis.