Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Implantable defibrillators. Sudden death: high risk].

D Lellouche1, P Pujadas-Berthault, N Elbaz

  • 1Service de Cardiologie, CHU Henri Mondor, 51, avenue de Mal de Lattre-deTassigny, F94010 Créteil.

Presse Medicale (Paris, France : 1983)
|June 14, 2001
PubMed
Summary

Sudden cardiac death remains a significant risk, particularly for those with heart failure. Implantable defibrillators significantly reduce mortality compared to drug therapies for high-risk individuals.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Evaluation of ownership of an implantable medical device by patients].

Annales pharmaceutiques francaises·2013
Same author

[Not Available].

Herzschrittmachertherapie & Elektrophysiologie·2009
Same author

Spontaneous polymorphic ventricular tachycardia recorded during an electroencephalogram in a patient with apparent epilepsy.

Heart (British Cardiac Society)·2004
Same author

[Electromechanical mapping of myocardial ischemia in coronary occlusion in the pig].

Archives des maladies du coeur et des vaisseaux·2003
Same author

[Atrial flutter with 1/1 nodo-ventricular conduction with amiodarone. From physiopathology to diagnosis].

Archives des maladies du coeur et des vaisseaux·2003
Same author

Single-lead VDD-pacing system incorporating high impedance stimulation: a multicentre study.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2002

Area of Science:

  • Cardiology
  • Sudden Cardiac Death Research
  • Medical Device Technology

Context:

  • Sudden cardiac death (SCD) incidence remains high, primarily linked to ischemic heart disease and heart failure.
  • Identifying high-risk populations is crucial for effective prevention strategies.
  • Automatic defibrillation, pioneered by Mirovski, is a key intervention.

Purpose:

  • To evaluate the effectiveness of automatic defibrillation in preventing sudden cardiac death.
  • To compare the mortality reduction efficacy of defibrillators versus pharmacological treatments.
  • To highlight risk markers for sudden cardiac death.

Summary:

  • Markers such as left ventricular dysfunction, functional class, and ventricular hyperexcitability identify individuals at high risk for SCD.
  • While drug treatments like beta-blockers, ACE inhibitors, and amiodarone show some efficacy, therapeutic trials indicate a significant superiority of defibrillation.
  • Defibrillation demonstrated a 20-46% greater reduction in mortality compared to drug treatments in post-infarction and heart failure patients.

Impact:

  • This research underscores the critical role of automatic defibrillators in managing high-risk cardiovascular patients.
  • The findings support the clinical implementation of defibrillators as a superior strategy for reducing SCD mortality.
  • Enhanced understanding of SCD risk factors and treatment efficacy can guide clinical decision-making and improve patient outcomes.

Related Experiment Videos