Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Evolution, language and analogy in functional genomics.

S A Benner1, E A Gaucher

  • 1Dept of Chemistry, NASA Astrobiology Institute, University of Florida, Gainesville, FL 32611-7200, USA. benner@chem.ufl.edu

Trends in Genetics : TIG
|June 22, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mars Extant Life: What's Next? Conference Report.

Astrobiology·2020
Same author

Hydroxymethanesulfonate from Volcanic Sulfur Dioxide: A "Mineral" Reservoir for Formaldehyde and Other Simple Carbohydrates in Prebiotic Chemistry.

Astrobiology·2019
Same author

Borate minerals stabilize ribose.

Science (New York, N.Y.)·2004
Same author

Detecting compensatory covariation signals in protein evolution using reconstructed ancestral sequences.

Journal of molecular biology·2002
Same author

Redesigning nucleic acids.

Pure and applied chemistry. Chimie pure et appliquee·2001
Same author

Quantitative analysis of receptors for adenosine nucleotides obtained via in vitro selection from a library incorporating a cationic nucleotide analog.

Journal of the American Chemical Society·2001
Same journal

The future of marsupial gene editing: What's in the (tool) pouch?

Trends in genetics : TIG·2026
Same journal

Genetic suppressors as new therapeutic targets for Mendelian diseases.

Trends in genetics : TIG·2026
Same journal

Beyond housekeeping: snRNA diversity, regulation, and human disease.

Trends in genetics : TIG·2026
Same journal

Rethinking mitochondrial metabolism: Intraindividual variability meets population constraints.

Trends in genetics : TIG·2026
Same journal

A role for epigenetics in rapid adaptation.

Trends in genetics : TIG·2026
Same journal

The myth of asexual fungi.

Trends in genetics : TIG·2026
See all related articles

Wittgenstein's theories on language and science reveal paradoxes hindering functional genomics. Addressing these linguistic paradoxes is crucial for unlocking the full potential of genomic sequence information.

Area of Science:

  • Philosophy of Science
  • Genomics
  • Bioinformatics

Background:

  • Ludwig Wittgenstein's philosophical work highlights the intrinsic link between scientific theory and language.
  • This connection is often overlooked in current genomics research.
  • Potential paradoxes identified by Wittgenstein may impede scientific progress in functional genomics.

Purpose of the Study:

  • To explore the relevance of Wittgenstein's linguistic paradoxes to contemporary functional genomics.
  • To argue that these paradoxes represent a significant, yet unaddressed, limitation in the field.
  • To advocate for the recognition and resolution of these paradoxes to advance genomic sequence extrapolation.

Main Methods:

  • Conceptual analysis of Wittgenstein's philosophical concepts.

Related Experiment Videos

  • Literature review of functional genomics and bioinformatics.
  • Application of philosophical paradoxes to current challenges in genomics.
  • Main Results:

    • Identified parallels between Wittgenstein's linguistic paradoxes and current limitations in functional genomics.
    • Demonstrated how a lack of addressing these paradoxes restricts the extrapolation of information from genomic sequences.
    • Highlighted the need for a paradigm shift in how language is considered within genomics.

    Conclusions:

    • Functional genomics is currently constrained by linguistic paradoxes, echoing Wittgenstein's century-old observations.
    • Resolving these paradoxes is essential for improving the predictive power and applicability of genomic data.
    • Future advancements in functional genomics depend on integrating philosophical insights into scientific practice.