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Published on: November 5, 2019
[Fulminant meningococcemia presenting as a gastroenteritis-like syndrome]
A Hussein1, Y Naschitz, D Yeshurun
1Depts. of Emergency Medicine and of Medicine A, Bnai Zion Medical Center and Bruce Rapport Faculty of Medicine, Haifa.
Abstract:
Neisseria meningitidis infection (meningococcemia) is very common throughout the world. It usually presents as meningitis or sometimes pharyngitis. A gastroenteritis-like syndrome, with diarrhea, vomiting and abdominal pain, may occur in children but is very rare in adults. Search of the medical literature revealed only 3 such cases, all in young adults. We report an 80-year-old woman who presented with fever, diarrhea and abdominal pain. Meningococcus infection was later suspected, and proved by culture. Although treatment was intensive and included ceftriaxone (Rocephin) and garamycin, she did not respond and died 40 hours after admission. We draw attention to the possibility that what is usually a common symptom can be the first presentation of a serious, often fatal condition.
Insights
Gastroenteritis symptoms like diarrhea and abdominal pain can signal a rare but serious Neisseria meningitidis infection (meningococcemia) in adults. This case highlights the importance of considering meningococcemia in elderly patients presenting with such symptoms, even if rare.
Area of Science:
- Infectious Diseases
- Internal Medicine
- Gastroenterology
Background:
- Neisseria meningitidis (meningococcus) commonly causes meningitis or pharyngitis globally.
- Gastrointestinal symptoms are an atypical presentation of meningococcemia, primarily observed in children.
- Literature review identified only three prior adult cases of meningococcal gastroenteritis, all in young adults.
Observation:
- An 80-year-old woman presented with fever, diarrhea, and abdominal pain.
- Meningococcus infection was suspected and subsequently confirmed by blood culture.
- Despite intensive treatment with ceftriaxone and gentamicin, the patient did not improve.
Findings:
- The patient succumbed to the infection 40 hours after admission.
- This case represents an extremely rare presentation of meningococcemia in an elderly adult.
- The clinical presentation mimicked a typical gastroenteritis syndrome.
Implications:
- Clinicians should consider meningococcemia in the differential diagnosis of unexplained gastroenteritis, particularly in elderly patients.
- Early recognition and treatment of meningococcemia are crucial due to its potential for rapid progression and high mortality.
- This case underscores the variability of Neisseria meningitidis presentation across different age groups.
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