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Pervasive developmental disorders in preschool children
1MRC Child Psychiatry Unit, Institute of Psychiatry/King's College London, Denmark Hill, London SE5 8AF, England.
Insights
This study found higher rates of pervasive developmental disorders (PDDs) in preschool children than previously reported. Further research is needed to determine if this reflects an actual increase in autism spectrum disorder incidence.
Area of Science:
- Pediatric Neurology
- Developmental Psychology
- Epidemiology
Background:
- Autism spectrum disorder prevalence is uncertain, with ongoing concerns about increasing incidence.
- Accurate epidemiological data is crucial for understanding and addressing developmental disorders.
Purpose of the Study:
- To estimate the prevalence of pervasive developmental disorders (PDDs) in a defined population of preschool-aged children.
- To provide updated epidemiological data on PDDs in early childhood.
Main Methods:
- A survey was conducted in Staffordshire, England, screening 15,500 children aged 2.5 to 6.5 years.
- Children with suspected PDDs underwent intensive assessment by a multidisciplinary team, including standardized diagnostic interviews and psychometric testing.
Main Results:
- The study identified 97 children with PDDs, estimating a prevalence of 62.6 per 10,000 children.
- Autistic disorder prevalence was 16.8 per 10,000, and other PDDs were 45.8 per 10,000.
- Associated conditions included mental retardation (25.8%) and medical conditions (9.3%).
Conclusions:
- PDD rates appear higher than previously documented in preschool populations.
- Current epidemiological limitations prevent definitive conclusions about increased incidence, necessitating further rigorous investigation.
- The findings highlight the significant needs of preschool children diagnosed with PDDs.
Context:
Prevalence rates of autism-spectrum disorders are uncertain, and speculation that their incidence is increasing continues to cause concern.
Objective:
To estimate the prevalence of pervasive developmental disorders (PDDs) in a geographically defined population of preschool children.
Design, Setting, And Participants:
Survey conducted July 1998 to June 1999 in Staffordshire, England. The area's 15 500 children aged 2.5 to 6.5 years were screened for developmental problems. Children with symptoms suggestive of a PDD were intensively assessed by a multidisciplinary team, which conducted standardized diagnostic interviews and administered psychometric tests.
Main Outcome Measure:
Prevalence estimates for subtypes of PDDs.
Results:
A total of 97 children (79.4% male) were confirmed to have a PDD. The prevalence of PDDs was estimated to be 62.6 (95% confidence interval, 50.8-76.3) per 10 000 children. Prevalences were 16.8 per 10 000 for autistic disorder and 45.8 per 10 000 for other PDDs. The mean age at diagnosis was 41 months, and 81% were originally referred by health visitors (nurse specialists). Of the 97 children with a PDD, 25.8% had some degree of mental retardation and 9.3% had an associated medical condition.
Conclusions:
Our results suggest that rates of PDD are higher than previously reported. Methodological limitations in existing epidemiological investigations preclude interpretation of recent high rates as indicative of increased incidence of these disorders although this hypothesis requires further rigorous testing. Attention is nevertheless drawn to the important needs of a substantial minority of preschool children.
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