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Calcifying odontogenic cyst. Report of two cases
B Sivapathasundharam1, S Rafiudeen
1Dept. of Oral Pathology, Meenakshi Ammal Dental College, Chennai, 102, India.
Summary
This study presents two rare cases of calcifying odontogenic cyst (COC), an uncommon jaw cyst. Histopathological examination confirmed the diagnosis, highlighting the controversial nature and classifications of this rare lesion.
Area of Science:
- Oral and Maxillofacial Pathology
- Developmental Odontogenic Cysts
Background:
- Calcifying odontogenic cyst (COC) is an extremely rare developmental odontogenic cyst, accounting for approximately 1% of all jaw cysts.
- First described by Gorlin in 1962, COC presents unique diagnostic challenges due to its controversial nature and varied classifications.
Observation:
- Two cases are presented: a 32-year-old female with a midline-crossing lower anterior swelling and a 29-year-old male with an upper anterior swelling.
- Radiographic findings included well-circumscribed radiolucency and opacities.
- Histopathological examination revealed characteristic features such as ghost cells and dentinoid tissue.
Findings:
- Histopathological analysis confirmed the diagnosis of calcifying odontogenic cyst.
- Immunohistochemical study for cytokeratin was also performed.
Implications:
- The presentation of these rare cases contributes to understanding COC variations.
- Discussion addresses controversies and proposed classifications for this rare odontogenic lesion.
