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[Interaction of lactoferrin with plasmid DNA studied by laser correlation spectroscopy]
I G Danilova1, N I Sinogeeva, M M Shavlovskiĭ
1St. Petersburg Institute of Nuclear Physics, Russian Academy of Sciences, Gatchina, 188300 Russia.
Biofizika
|July 14, 2001
Abstract:
The interactions of lactoferrin with plasmid DNAs substantially differing in the number of affine regions were studied. The dissociation constants for protein-nucleic acid complexes were determined. The possibility of standardizing the conditions for preparing multicomponent systems for gene-substituting therapy by laser correlation spectroscopy is discussed.