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Related Experiment Videos

[Septic shock due to pyonephrosis-calculosa: a case report].

A Takao1, Y Nakayama, T Ichikawa

  • 1Department of Urology, Hiroshima City Hospital.

Nihon Hinyokika Gakkai Zasshi. the Japanese Journal of Urology
|July 14, 2001
PubMed
Summary

A severe kidney infection (pyonephrosis) with a stone caused septic shock in a 69-year-old woman. Prompt nephrectomy and intensive treatment successfully resolved her multiple organ failure and improved her condition.

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Area of Science:

  • Nephrology
  • Critical Care Medicine
  • Urology

Background:

  • Septic shock is a life-threatening condition requiring prompt intervention.
  • Pyonephrosis-calculosa, a severe kidney infection with stones, can lead to systemic complications.
  • Multiple organ failure (MOF) presents a significant challenge in critical care.

Observation:

  • A 69-year-old female presented with high-grade fever and clouded consciousness, indicative of severe illness.
  • Clinical data revealed septic shock, disseminated intravascular coagulation (DIC), and MOF.
  • Imaging showed left hydronephrosis, a peri-renal cystic mass, and a left ureteral stone.

Findings:

  • The patient was diagnosed with septic shock secondary to pyonephrosis-calculosa and a peri-renal abscess.

Related Experiment Videos

  • A left nephrectomy was performed, alongside endotoxin removal therapy and continuous hemodiafiltration (CHDF).
  • Post-intervention, the patient's morbidities significantly improved, indicating treatment efficacy.

    • Implications:

    • Nephrectomy combined with intensive medical management is a viable treatment for severe pyonephrosis-calculosa with abscess and MOF.
    • Early diagnosis and aggressive intervention are crucial for managing complex urosepsis cases.
    • Endotoxin removal and CHDF may play a supportive role in stabilizing patients with septic shock and MOF.