Related Experiment Video
Updated: Apr 21, 2026
08:30
Mouse Models of Epididymitis Induced by Pathogen-Associated Molecular Patterns
Published on: December 12, 2025
452
[CASE OF EPIDIDYMITIS LEADING TO DIAGNOSIS OF INCOMPLETE BEHCET'S DISEASE]
Takahiro Fukuda1, Kousuke Nishizaki1, Koji Fukui1
1Department of Urology, Takarazuka City Hospital.
Summary
A man with persistent epididymitis symptoms was ultimately diagnosed with incomplete Behcet's disease. Colchicine treatment led to significant symptom relief, highlighting its efficacy in managing this rare condition.
Area of Science:
- Rheumatology
- Urology
- Ophthalmology
Background:
- A 50-year-old male presented with symptoms initially diagnosed as acute epididymitis.
- Standard antibiotic treatments (levofloxacin, ceftriaxone) failed to resolve the condition.
- Persistent symptoms and fever of unknown origin prompted further investigation.
Purpose of the Study:
- To investigate the underlying cause of refractory epididymitis and fever of unknown origin.
- To evaluate the diagnostic utility of advanced imaging and rheumatological assessments.
- To determine the effectiveness of colchicine in suspected Behcet's disease.
Main Methods:
- Clinical examination and standard urine analysis.
- Antibiotic therapy and imaging studies (CT, MRI).
- Rheumatological workup including autoantibody tests, gallium scintigraphy, and fundus angiography.
- Initiation of colchicine treatment based on clinical suspicion.
Main Results:
- Imaging revealed only epididymal swelling, ruling out abscess.
- Gallium scintigraphy indicated inflammatory changes in multiple joints.
- Fundus angiography showed characteristic fern-like fluorescent leakage.
- Colchicine treatment resulted in dramatic symptom improvement.
- Diagnosis of incomplete Behcet's disease was confirmed by oral ulcers and vascular findings.
Conclusions:
- Incomplete Behcet's disease can present with urological symptoms mimicking epididymitis.
- A multidisciplinary approach involving urology, rheumatology, and ophthalmology is crucial for diagnosis.
- Colchicine is an effective treatment for managing symptoms in incomplete Behcet's disease.
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