Related Experiment Video
Updated: Oct 5, 2026

Rodent Model of Intestinal Ischemia-Reperfusion Injury via Occlusion of the Superior Mesenteric Artery
Published on: October 20, 2023
[Intestinal failure]
1Service d'hépato-gastro-entérologie et nutrition Hôpital Bichat-Claude-Bernard 75877 Paris. pascal.crenn@bch.ap-hop-paris.fr
Abstract:
Intestinal failure is defined as the reduction in the functioning gut mass below the minimal amount necessary for the absorption of nutrients and a normal nutritional status. The main cause of chronic intestinal failure in adults is short bowel syndrome secondary to mesenteric ischemia. In short bowel the remnant bowel length is inferior to 200 cm. The two other causes of intestinal failure are extensive small bowel mucosal diseases and chronic intestinal pseudo-obstruction. The reference treatment of severe chronic intestinal failure is home parenteral nutrition. The main alternate for irreversible intestinal failure is small bowel transplantation, isolated or combined to liver transplantation.
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