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Dimethyl sulfoxide: recent pharmacological and toxicological research
1Department of Veterinary Medicine, King Saud University, Buraydah, Saudi Arabia.
Abstract:
A survey of the literature published in the past 2 decades on the basic pharmacology, therapeutic uses and toxicity of dimethyl sulfoxide (DMSO) is presented. A salient pharmacological action of DMSO is its ability to scavenge oxygen-free radicals implicated in xenobiotic-induced tissue damages when given before, during or several hours after the tissue insult. More trials with DMSO in diseases and conditions caused by oxygen-free radicals are warranted.