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[Bleomycin prick in therapy-resistant verruca vulgaris]
1Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität München, Frauenlobstrasse 9-11, 80337 München.
Summary
Bleomycin injections effectively treated a patient with severe, therapy-resistant common warts on her hands and feet. This method offers a promising alternative for difficult wart cases unresponsive to standard treatments.
Area of Science:
- Dermatology
- Immunology
Background:
- Common warts are often resistant to standard treatments like cryotherapy and salicylic acid.
- Intralesional bleomycin has been a recognized treatment for warts since 1970.
Observation:
- A 27-year-old woman with Sharp's syndrome on immunosuppressants presented with nine years of therapy-resistant palmar and plantar warts.
- The patient had failed multiple conventional therapies.
Findings:
- A bleomycin-prick technique using a bifurcated needle delivered bleomycin sulfate (1 mg/ml) into the warts.
- Almost complete remission was achieved after 16 treatment sessions.
Implications:
- The bleomycin-prick technique shows significant efficacy for recalcitrant common warts, even in immunocompromised patients.
- This method provides a viable treatment option for difficult-to-treat warts unresponsive to conventional therapies.