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Related Experiment Videos

Specific immunotherapy in rhinitis and asthma.

J Bousquet1, P Demoly, F B Michel

  • 1Service des Maladies Respiratoires, INSERM U454 Hĵpital Arnaud de Villeneuve, Montepelier, France. bousquet@montp.inserm.fr

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
|July 31, 2001
PubMed
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Allergen-specific immunotherapy (SIT) effectively treats allergic rhinitis and asthma. Emerging evidence suggests SIT may also prevent new allergies and alter the natural course of asthma, especially when initiated early.

Area of Science:

  • Allergy and Immunology
  • Respiratory Medicine

Background:

  • Asthma and rhinitis frequently coexist, with rhinitis often preceding asthma.
  • Allergic diseases share common inflammatory pathways.

Purpose of the Study:

  • To review the efficacy of immunotherapy for combined nasal and lung symptoms.
  • To explore the preventive potential of allergen-specific immunotherapy (SIT) on rhinitis and asthma.
  • To discuss SIT's role in altering the natural course of allergic disease.

Main Methods:

  • Literature review of studies on allergen-specific immunotherapy (SIT) for allergic rhinitis and asthma.
  • Synthesis of existing research and expert opinion.

Main Results:

  • SIT is effective for treating existing allergic rhinitis and asthma.

Related Experiment Videos

  • Evidence suggests SIT can prevent the development of new allergic sensitizations.
  • Immunotherapy has been shown to alter the natural course of allergy in children.

    • Conclusions:

    • SIT is the only current treatment that may modify disease progression by preventing new sensitivities or altering asthma's natural history.
    • Early initiation of SIT in patients with allergic rhinoconjunctivitis may prevent asthma development.
    • Starting SIT upon diagnosis is crucial for modifying long-term allergic inflammation.