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Related Experiment Videos

Ginger, fat and fibrinolysis.

S K Verma1, A Bordia

  • 1Department of Medicine and Indigenous Drug Research Centre, R.N.T. Medical College, Udaipur-313 001.

Indian Journal of Medical Sciences
|August 3, 2001
PubMed
Summary

A high-fat meal reduced blood clot dissolving activity. However, adding ginger powder to the meal significantly boosted this activity, highlighting ginger's potential health benefits.

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Area of Science:

  • Cardiovascular Science
  • Nutritional Science
  • Pharmacology

Background:

  • Dietary fats can impact blood coagulation and fibrinolysis.
  • Fibrinolytic activity is crucial for preventing excessive blood clot formation.
  • Ginger is a traditional spice with potential medicinal properties.

Purpose of the Study:

  • To investigate the effect of a high-fat meal on fibrinolytic activity.
  • To determine if ginger supplementation can mitigate the negative effects of dietary fat on fibrinolysis.
  • To explore ginger's potential as a fibrinolytic enhancer.

Main Methods:

  • 30 healthy adults were given a 50 gm fat meal.
  • Fibrinolytic activity was measured before and after the meal.
  • A subset of participants received 5 gm of ginger powder with the fatty meal.

Main Results:

  • The high-fat meal significantly decreased fibrinolytic activity (P < 0.001).
  • Supplementation with 5 gm of ginger powder prevented this decrease.
  • Ginger significantly increased fibrinolytic activity compared to the fatty meal alone (P < 0.001).

Conclusions:

  • High-fat meals can impair the body's natural clot-dissolving mechanisms.
  • Ginger powder demonstrates significant fibrinolytic-enhancing properties.
  • Ginger may offer therapeutic benefits by improving cardiovascular health through enhanced fibrinolysis.

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