Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Trials01:16

Clinical Trials

11.0K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
11.0K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

503
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
503
Ethics in Research01:56

Ethics in Research

26.0K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
26.0K
Data Collection by Experiments01:13

Data Collection by Experiments

27.8K
Data collection is a systematic method of obtaining, observing, measuring, and analyzing accurate information. An experimental study is a standard method of data collection that involves the manipulation of the samples by applying some form of treatment prior to data collection. It refers to manipulating one variable to determine its changes on another variable. The sample subjected to treatment is known as “experimental units.”
An example of the experimental method is a public...
27.8K
Study Designs in Epidemiology01:20

Study Designs in Epidemiology

1.3K
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
1.3K
The Scientific Method in Nursing Process01:18

The Scientific Method in Nursing Process

19.0K
The scientific method provides the foundation for any research. It is the most reliable and objective of all forms of gaining knowledge and guides in applying research-based evidence in practice and conducting future research.
When using research findings to change practice, one must understand the process used to guide a study. The scientific method is a systematic, step-by-step process that supports the data's validity, reliability, and generalizability. As a result, findings can be...
19.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[A critical consideration of alternative methods is useful].

Der Nervenarzt·2019
Same author

[The role of psychopharmacotherapy in the development of social psychiatry in Germany].

Der Nervenarzt·2017
Same author

[Psychiatrists between oath to secrecy and duty to warn].

Der Nervenarzt·2016
Same author

[Research on humans suffering from dementia].

Der Nervenarzt·2015
Same author

[Physicians conscience and Zeitgeist].

Der Nervenarzt·2014
Same author

[Bonhoeffer's position on sterilization of the mentally ill].

Der Nervenarzt·2014
Same journal

[Rare hereditary and acquired diseases with parkinson's syndrome].

Fortschritte der Neurologie-Psychiatrie·2026
Same journal

[Digital transformation in multiple sclerosis: Advances in diagnostics, monitoring and patient-centred care].

Fortschritte der Neurologie-Psychiatrie·2026
Same journal

[Dementia with Lewy bodies].

Fortschritte der Neurologie-Psychiatrie·2026
Same journal

[Impact of the PEPP reimbursement system and other developments on inpatient care of general psychiatry patients 2005 to 2022: a retrospective analysis].

Fortschritte der Neurologie-Psychiatrie·2026
Same journal

[The pathology of the brain eating amoeba Naegleria fowleri].

Fortschritte der Neurologie-Psychiatrie·2026
Same journal

[Chronic vestibular syndromes: Correct diagnosis and treatment].

Fortschritte der Neurologie-Psychiatrie·2026
See all related articles

Related Experiment Video

Updated: Mar 1, 2026

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
11:21

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

8.9K

[Clinical research methods].

H Helmchen1

  • 1Psychiatrische Klinik und Poliklinik, Freien Universität Berlin.

Fortschritte Der Neurologie-Psychiatrie
|August 8, 2001
PubMed
Summary
This summary is machine-generated.

This study outlines essential clinical research components, from precise questions and empirical hypotheses to data analysis and publication. It emphasizes practical considerations like sample size, control groups, and ethical implications for successful research design.

More Related Videos

Neuroimaging Field Methods Using Functional Near Infrared Spectroscopy NIRS Neuroimaging to Study Global Child Development: Rural Sub-Saharan Africa
08:10

Neuroimaging Field Methods Using Functional Near Infrared Spectroscopy NIRS Neuroimaging to Study Global Child Development: Rural Sub-Saharan Africa

Published on: February 2, 2018

15.7K
A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

13.6K

Related Experiment Videos

Last Updated: Mar 1, 2026

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
11:21

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

8.9K
Neuroimaging Field Methods Using Functional Near Infrared Spectroscopy NIRS Neuroimaging to Study Global Child Development: Rural Sub-Saharan Africa
08:10

Neuroimaging Field Methods Using Functional Near Infrared Spectroscopy NIRS Neuroimaging to Study Global Child Development: Rural Sub-Saharan Africa

Published on: February 2, 2018

15.7K
A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

13.6K

Area of Science:

  • Clinical Research Methodology
  • Biomedical Research Design

Context:

  • Covers essential components of clinical research design.
  • Addresses practical aspects of research execution and framework.

Purpose:

  • To provide a comprehensive overview of clinical research methodology.
  • To guide researchers in designing and conducting empirical studies.

Summary:

  • Discusses research questions, testable hypotheses, sample size estimation, and control group selection.
  • Details methods for assessing psychopathological phenomena, data analysis, and publication preparation.
  • Examines research project timelines, patient access, funding, and ethical considerations.

Impact:

  • Aims to improve the rigor and efficiency of clinical research.
  • Contributes to the standardization of best practices in scientific inquiry.