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[Changes in metabolic parameters and microalbuminuria in patients with type 2 diabetes treated with acarbose]
E González Sarmiento1, P Ergueta Martín, I Fernández Martínez
1Departamentos de Medicina Interna y Endocrinología, Hospital Universitario, Valladolid.
Objective:
To determinate the influence of the acarbosa and microalbuminuria on metabolic parameters in patients diabetics type 2.
Research Design And Methods:
We are studied 92 patients with diabetes type 2, treated with Acarbose alone or with insuline or oral anti-diabetics We are determined the values of HbA1c, total cholesterol, HDL, LDL, triglycerides and microalbuminuria, before and after or the treatment with acarbose.
Results:
The patients presented globally a statistically significant improvement in the levels of Hb A1 c, triglycerides and microalbuminuria. In the group treatise with 300 mg/day of acarbose it was observed a significant decrease of the values of Hb A1c and triglycerides independently of the associated treatment. In the group treated with 150 mg/day the improvement only it was statistically significant for the levels of Hb A1c.
Conclusions:
The treatment with acarbose produces an improvement in the levels of Hb A1c independently of the administered dose and of the triglycerides in patients treated with 300 mg/day without relation to associated treatments. Therefore, he acarbose win be considered an effective medication to improve the metabolic control to prevent the cardiovascular risk in those patients.
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