Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Human herpesvirus 6.

M T Caserta1, D J Mock, S Dewhurst

  • 1Department of Pediatrics, University of Rochester Medical Center, Rochester, NY 14642, USA.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|August 21, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pharmacologic profiling reveals lapatinib as a novel antiviral against SARS-CoV-2 in vitro.

Virology·2021
Same author

Evaluating the Antimicrobial Properties of Commercial Hand Sanitizers.

mSphere·2021
Same author

Mechanisms of head stability during gait initiation in young and older women: A neuro-mechanical analysis.

Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology·2017
Same author

Orthodontics: Allergic to the orthodontist?

British dental journal·2016
Same author

Effect of exercise training on neuromuscular function of elbow flexors and knee extensors of type 2 diabetic patients.

Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology·2015
Same author

In vivo gene delivery and expression by bacteriophage lambda vectors.

Journal of applied microbiology·2007
Same journal

Reconsidering ambiguous language in infectious disease consult recommendations.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Antibiotic Treatment Duration for Uncomplicated Monomicrobial Enterococcal Bloodstream Infection: A Multicenter Target Trial Emulation.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Larger Blood Volume Increases Detection of Fastidious Mycobacteria and Fungi in Blood Culture.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Anticalcitonin: Limited utility of a context-dependent biomarker demonstrated in another real-world data set.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Procalcitonin Testing in Community-Acquired Pneumonia.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Wanted: A Relevant Correlate of Protection for Dengue Vaccines.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
See all related articles

Human herpesvirus 6 (HHV-6) is a common virus causing childhood illness. Reactivation can lead to serious conditions in immunocompromised individuals, including encephalitis and potentially multiple sclerosis.

Area of Science:

  • Virology
  • Immunology
  • Infectious Diseases

Background:

  • Human herpesvirus 6 (HHV-6) was discovered in 1986, initiating a new era in herpesvirology.
  • HHV-6 is ubiquitous, establishing lifelong latent infections in hosts.
  • Primary HHV-6 infection commonly affects infants and young children, causing roseola infantum or febrile illness.

Purpose of the Study:

  • To discuss the key properties of HHV-6.
  • To explore the association of HHV-6 with human diseases.
  • To examine the pathobiological significance of HHV-6 reactivation.

Main Methods:

  • Literature review of HHV-6 properties and associated diseases.
  • Analysis of HHV-6's role in primary infections and reactivation.
  • Discussion of pathobiological mechanisms and clinical implications.

Related Experiment Videos

Main Results:

  • HHV-6 efficiently infects young children, leading to common febrile illnesses.
  • Reactivation of HHV-6 in immunocompromised individuals is linked to severe diseases like encephalitis.
  • A tentative association between HHV-6 and multiple sclerosis has been noted.

Conclusions:

  • HHV-6 is a significant human pathogen with diverse clinical manifestations.
  • Understanding HHV-6 properties and reactivation is crucial for managing associated diseases.
  • Further research is needed to clarify the role of HHV-6 in chronic conditions like multiple sclerosis.