Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Maintaining and incrementally revalidating a computer-based clinical guideline: a case study.

P L Miller1, S J Frawley, F G Sayward

  • 1Center for Medical Informatics, Yale University School of Medicine, P.O. Box 208009, New Haven, CT 06520-8009, USA. perry.miller@yale.edu

Journal of Biomedical Informatics
|August 23, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Medical Informatics Training at Yale University School of Medicine.

Yearbook of medical informatics·2016
Same author

ATTENDING: Critiquing a Physician's Management Plan.

IEEE transactions on pattern analysis and machine intelligence·2011
Same author

Approaches and informatics tools to assist in the integration of similar clinical research questionnaires.

Methods of information in medicine·2004
Same author

TrialDB: A web-based Clinical Study Data Management System.

AMIA ... Annual Symposium proceedings. AMIA Symposium·2004
Same author

ALFRED: the ALelle FREquency Database. Update.

Nucleic acids research·2003
Same author

Issues in computer-based decision support in public health illustrated using projects involving childhood immunization.

Journal of public health management and practice : JPHMP·2001
Same journal

Evaluation of temporal preservation in synthetic longitudinal patient data.

Journal of biomedical informatics·2026
Same journal

ARKE: An ontology-driven framework for automated mapping of local radiology procedure terms to the LOINC-RadLex playbook using large language model.

Journal of biomedical informatics·2026
Same journal

A validation-driven training controller for cross-lingual biomedical NER via reinforcement learning-based adaptive loss weighting.

Journal of biomedical informatics·2026
Same journal

ASP-HR: An Adaptive Spatial Perception and Hierarchical Reasoning mechanism for document-level biomedical relation extraction.

Journal of biomedical informatics·2026
Same journal

Beyond Accuracy: Safety-Centered guidelines for the evaluation of LLM-based therapy recommendation systems for chronic multimorbidity patients.

Journal of biomedical informatics·2026
Same journal

DeepEN: A deep reinforcement learning framework for personalized enteral nutrition in critical care.

Journal of biomedical informatics·2026
See all related articles

Maintaining complex computer-based clinical guidelines, like childhood immunization schedules, involves managing national changes and local adaptations. This study details logic issues encountered and proposes domain knowledge for automated validation.

Area of Science:

  • Health Informatics
  • Computer Science
  • Public Health

Background:

  • Computer-based clinical guidelines are essential for healthcare delivery.
  • Maintaining the accuracy and relevance of these guidelines is challenging due to evolving medical recommendations and local healthcare needs.
  • The IMM/Serve system for childhood immunization serves as a practical case study for these challenges.

Purpose of the Study:

  • To explore the complexities of maintaining logic in computer-based clinical guidelines.
  • To document issues arising from national recommendation changes and local system customizations.
  • To investigate the role of domain knowledge in validating guideline logic.

Main Methods:

  • A longitudinal log was maintained for over 1.5 years.

Related Experiment Videos

  • Data collected included national immunization recommendation changes, local IMM/Serve logic customizations, and logic problems encountered.
  • Analysis focused on the nature of these changes, customizations, and problems.
  • Main Results:

    • Significant challenges exist in updating and customizing clinical guideline logic.
    • Specific types of logic problems were identified during the adaptation process.
    • The study highlights the practical difficulties in ensuring guideline accuracy over time.

    Conclusions:

    • Maintaining computer-based clinical guidelines requires robust strategies for managing updates and customizations.
    • Domain knowledge can potentially aid in the automated validation of guideline logic.
    • The findings offer insights into the real-world issues of clinical decision support system maintenance.