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Tuberculosis and aging: a global health problem.

S Rajagopalan1

  • 1Department of Internal Medicine, Division of Infectious Disease, Charles R. Drew University of Medicine and Science, Martin Luther King, Jr./Drew Medical Center, Los Angeles, CA 90059, USA. shrajago@cdrewu.edu

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|August 31, 2001
PubMed
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Tuberculosis (TB) remains a global health challenge, particularly affecting the elderly. Delayed diagnosis due to atypical symptoms in older adults leads to increased illness and death from this treatable infection.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Geriatrics

Background:

  • Tuberculosis (TB) is a declared global emergency by the World Health Organization.
  • Despite control initiatives, TB continues to impact vulnerable populations, notably the elderly (age > or =65 years).
  • Tuberculosis in aging adults presents unique clinical and epidemiological challenges.

Purpose of the Study:

  • To highlight the persistent challenge of tuberculosis in the elderly population.
  • To underscore the impact of atypical clinical manifestations on diagnosis and treatment outcomes.
  • To emphasize the need for a high index of suspicion for TB in older adults.

Main Methods:

  • This study is a review of clinical and epidemiological challenges of tuberculosis in the elderly.

Related Experiment Videos

  • Analysis of factors complicating TB management in aging adults.
  • Synthesis of current understanding of TB presentation in older individuals.

    • Main Results:

    • Atypical clinical presentations of TB in the elderly can delay diagnosis and treatment initiation.
    • Older adults experience higher rates of morbidity and mortality from tuberculosis.
    • Factors such as underlying illnesses, weakened immune function, adverse drug reactions, and institutionalization complicate TB management.

    Conclusions:

    • A high index of suspicion for tuberculosis is crucial in the elderly population.
    • Prompt diagnosis and treatment are essential to reduce morbidity and mortality.
    • Further research and tailored strategies are needed for effective TB control in aging adults.