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[Mesenteric lymph nodes in rats exposed to emotional stress]
M P Sapin1, E V Koplik, D B Nikitiuk
1Department of Human Anatomy, I.M. Sechenov Moscow Medical Academy and P.K. Anokhin Scientific Research Institute.
Abstract:
Structural and functional peculiarities of mesenteric lymph nodes were studied in 40 stressed August rats using micro anatomical methods. The stress was induced by limitation of any movement for 5 hrs every day. Peculiarities and intensity of modifications demonstrated was dependent on duration of stress actions. Significant decrease of cortical substance area, its lymphoid nodules length and width and germinal centre area, fraction of large, medium and small lymphocytes was observed following 5 hrs of the experiment, which was combined with expansion of the area, occupied by medullar substance. On the 2nd d of 5 hrs experiment cortical substance area was widened (on histological section), the number and sizes of lymphoid nodules grew up and lymphoid nodules appeared in medullar bands. On the 3rd experimental day mesenteric lymph node structure gradually restored. It showed control values on the 6th experimental day.