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Analgesic, diuretic, and anti-inflammatory principle from Scoparia dulcis
M Ahmed1, H A Shikha, S K Sadhu
1Department of Pharmacy, University of Dhaka, Dhaka, Bangladesh. mua@du.bangla.net
Die Pharmazie
|September 6, 2001
Abstract:
Scoparinol, a diterpene, isolated from Scoparia dulcis showed significant analgesic (p < 0.001) and anti-inflammatory activity (p < 0.01) in animals. A sedative action of scoparinol was demonstrated by a marked potentiation of pentobarbital-induced sedation with a significant effect on both onset and duration of sleep (p < 0.05). Measurement of urine volume after administration of scoparinol indicated its significant diuretic action.