Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Biochemical and hematologic changes after short-term space flight.

C S Leach1

  • 1NASA/Johnson Space Center, Houston, TX 77058.

Microgravity Quarterly : MGQ
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Collagen cross-link excretion during space flight and bed rest.

The Journal of clinical endocrinology and metabolism·1998
Same author

Regulation of body fluid volume and electrolyte concentrations in spaceflight.

Advances in space biology and medicine·1997
Same author

Regulation of body fluid compartments during short-term spaceflight.

Journal of applied physiology (Bethesda, Md. : 1985)·1996
Same author

Short-term space flight on nitrogenous compounds, lipoproteins, and serum proteins.

Journal of clinical pharmacology·1994
Same author

Changes in total body water during spaceflight.

Journal of clinical pharmacology·1991
Same author

Metabolic changes observed in astronauts.

Journal of clinical pharmacology·1991
Same journal

Telescience for the reduced gravity flight experiments.

Microgravity quarterly : MGQ·1997
Same journal

Preparatory tests for immunodetection of microtubules in protoplasts during IML-2.

Microgravity quarterly : MGQ·1994
Same journal

Kinetics of stipe gravitropism in the mushroom fungus Coprinus cinereus under the conditions of microgravity simulation provided by clinostat treatment.

Microgravity quarterly : MGQ·1994
Same journal

Gravitational biology of mushrooms: a flow-chart approach to characterising processes and mechanisms.

Microgravity quarterly : MGQ·1994
Same journal

An overview of the cosmic dust analogue material production in reduced gravity: the STARDUST experience.

Microgravity quarterly : MGQ·1993
Same journal

Adaptative responses of tobacco callus cells to simulated microgravity by compensation.

Microgravity quarterly : MGQ·1993
See all related articles

Astronaut blood analysis reveals distinct physiological changes after spaceflight. Short-term flights elevated angiotensin I and aldosterone, while longer missions showed delayed responses and decreased red blood cells.

Area of Science:

  • Space medicine
  • Human physiology in space
  • Clinical laboratory science

Background:

  • Understanding physiological adaptations to spaceflight is crucial for astronaut health.
  • Previous studies on Skylab missions provided insights into long-duration spaceflight effects.
  • Space Shuttle missions offer opportunities to study shorter-duration spaceflight impacts.

Purpose of the Study:

  • To compare clinical laboratory data from astronauts after short-term Space Shuttle flights with data from longer Skylab missions.
  • To identify specific biomarkers and physiological responses affected by spaceflight duration.
  • To investigate the influence of countermeasures and mission specifics on astronaut health.

Main Methods:

  • Analysis of astronaut blood samples collected pre- and post-flight.
Keywords:
NASA Center JSCNASA Discipline Number 00-00NASA Discipline Number 18-10NASA Discipline Regulatory PhysiologyNASA Program FlightNASA Program Space Physiology and Countermeasures

Related Experiment Videos

  • Statistical comparison using paired t-test and Wilcoxon signed-rank test.
  • Comparison of Space Shuttle (approx. 6 days) and Skylab (approx. 28, 59, 84 days) flight data.

    • Main Results:

    • Angiotensin I and aldosterone elevated post-Shuttle; angiotensin I response delayed post-Skylab.
    • Magnesium and uric acid decreased post-Shuttle and Skylab; serum calcium unchanged post-Shuttle.
    • Creatine phosphokinase reduced post-Shuttle (likely due to exercise countermeasures), but not post-Skylab.
    • Red blood cell concentration increased post-Shuttle, decreased post-Skylab; reticulocyte count decreased in both.
    • Total cholesterol unchanged, LDL-C increased, HDL-C decreased post-Shuttle; serum ferritin and platelets elevated post-Shuttle.

    Conclusions:

    • Spaceflight duration significantly influences hormonal and hematological parameters.
    • Reduced red blood cell mass appears linked to suppressed production rather than increased destruction.
    • Differences in responses between short- and long-term flights may be attributed to mission duration, countermeasures, spacecraft, and landing procedures.