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[Microorganisms and man. Various characteristics of their coexistence at present]
Iu L Shevchenko1, G G Onishchenko
1Ministry of Health of the Russian Federation, Moscow, Russia.
Abstract:
Modern data of literature on microbial associations and their role in human health and diseases are presented. As pointed out in this work, the characteristic feature of the XX century is the emergence and the re-emergence of 36 new infections. The emergence of many infections is associated with such factors as the increased migration of the population, ecological environmental disasters, etc. Grounds for a new view on the etiology of a number of chronic somatic diseases are given. The task of preparation development for the immunoprophylaxis of 25-30 infections has been set by WHO as its target for the year 2025. Prospects of new approaches to the development of new generation vaccines against bacterial, viral and parasitic infections, including HIV/AIDS, tuberculosis, virus hepatitides, malaria, etc., are shown.
Insights
Microbial associations impact human health, with 36 new infections emerging in the 20th century due to factors like migration. New vaccines are crucial for preventing infectious diseases by 2025.
Area of Science:
- Microbiology and Immunology
- Infectious Diseases
- Public Health
Context:
- The 20th century witnessed the emergence and re-emergence of 36 new infectious diseases.
- Factors such as increased population migration and ecological disasters contribute to disease spread.
- There is a growing understanding of microbial associations' role in human health and chronic diseases.
Purpose:
- To present modern literature data on microbial associations and their significance in human health and disease.
- To provide grounds for a new perspective on the etiology of chronic somatic diseases.
- To highlight the prospects of novel vaccine development for various infections.
Summary:
- The abstract reviews microbial associations and their link to human health and disease.
- It discusses the rise of new infections in the 20th century, driven by global changes.
- The text also explores the potential for new vaccine generations to combat bacterial, viral, and parasitic diseases, aligning with WHO's 2025 immunoprophylaxis goals.
Impact:
- Informs the development of new vaccines against critical infectious diseases like HIV/AIDS, tuberculosis, and malaria.
- Supports a paradigm shift in understanding the causes of chronic somatic diseases.
- Contributes to public health strategies for infectious disease prevention and control.