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[Ossifying fibromyxoid tumor of soft parts]
Background:
OMFT are nearly always benign, usually presented in soft tissue, of uncertain origin and tend to relapse. They are regarded as neoplasms of the adult, only three cases of children have been reported so far.
Patient:
A case of a 12-year-old boy is presented, for the first time, with an OMFT in the nasal cavity and the paranasal sinus. The diameter measured 9 centimetres. Histologically the tumor consisted of a myxoid matrix and showed areas of metaplastic bone. Most of the cells showed a spindleform and sometimes polymorphic hyperchromatic nuclei. The tumor expressed S-100 protein and vimentin. The cellularity was moderately high, the mitotic rate was very low.
Conclusions:
OMFT are rare neoplasms, the diagnosis should be verified histopathologically. Complete excision should be performed. A clinical follow-up is necessary.
Insights
Odontogenic Myxoma of the Jaw (OMFT) are rare benign tumors. This case highlights a large OMFT in a child
Area of Science:
- Oral and Maxillofacial Pathology
- Pediatric Neoplasms
Background:
- Odontogenic Myxoma of the Jaw (OMFT) are benign soft tissue neoplasms of uncertain origin.
- OMFT typically affect adults, with only three pediatric cases previously reported.
- These tumors have a tendency for recurrence after treatment.
Observation:
- A 12-year-old boy presented with a large, 9 cm OMFT in the nasal cavity and paranasal sinus.
- Histopathological examination revealed a myxoid matrix with metaplastic bone.
- Tumor cells exhibited spindle shapes, hyperchromatic nuclei, and expressed S-100 protein and vimentin.
Findings:
- The tumor demonstrated moderate cellularity and a low mitotic rate.
- Immunohistochemistry confirmed the expression of S-100 protein and vimentin.
- This represents the first reported case of OMFT in the nasal cavity and paranasal sinus in a pediatric patient.
Implications:
- Accurate histopathological diagnosis is crucial for managing OMFT.
- Complete surgical excision is the recommended treatment approach.
- Long-term clinical follow-up is essential due to the potential for recurrence.
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