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Updated: Jul 17, 2026

Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations
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Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations

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Computational models of normal and abnormal action potential propagation in cardiac tissue: linking experimental and

R H Clayton1

  • 1School of Biomedical Sciences, University of Leeds, UK. richard@cbiol.leeds.ac.uk

Physiological Measurement
|September 15, 2001
PubMed

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Action Potential01:14

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The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase of...
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Cardiac action potentials are essential for proper heart function, enabling the rhythmic contractions needed for adequate blood circulation. Nodal cells and Purkinje fibers, specialized for electrical conduction, generate these action potentials.
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