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Genetic Modification and Recombination of Salivary Gland Organ Cultures
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Published on: January 28, 2013

Strand-specific postreplicative processing of mammalian telomeres.

S M Bailey1, M N Cornforth, A Kurimasa

  • 1Bioscience Division, Los Alamos National Laboratory, Los Alamos, NM 87544, USA.

Science (New York, N.Y.)
|September 29, 2001
PubMed
Summary

Telomeres protect chromosome ends. Telomeric repeat binding factor 2 (TRF2) and DNA-dependent protein kinase (DNA-PK) are crucial for telomere function, with TRF2-mediated end-capping occurring post-replication on leading-strand synthesized telomeres.

Keywords:
Non-programmatic

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