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[Acute deep venous thrombosis and PET scanning with 2-fluoro-2-deoxy-D-glucose, FDG]
R B Jensen1, J Mortensen, M Dreyer
1H:S Rigshospitalet, klinisk fysiologi og nuklearmedicinsk klinik, PET og cyklotron-enheden.
Unlabelled:
A 30-year-old woman with a history of malignant non-Hodgkin lymphoma with a bulky tumour on the right thigh, primarily treated with high-dose chemotherapy and involving field radiation, developed a deep venous thrombosis (DVT) in her right leg two weeks after the end of therapy. Positron emission tomography with fluorine-18 flourodeoxyglucose (FDG PET) was performed to assess the response of the lymphoma to therapy. The PET scan showed several sites of pathological, high tracer uptake corresponding to residual lymphoma, but also intense activity in the right calf correlating to the deep veins located peripheral to the site of DVT. FDG PET performed two months later showed no pathological FDG uptake in this area.
Conclusion:
Acute DVT may cause pathological uptake of FDG and should therefore be considered a possible pitfall in the interpretation of FDG PET.