Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Setting the stage.

M J Schreiber1

  • 1Department of Nephrology and Hypertension, Cleveland Clinic Foundation, Cleveland, OH 44195, USA. schreim@ccf.org

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
|October 17, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Overweight, obesity and intentional weight loss in chronic kidney disease: NHANES 1999-2006.

International journal of obesity (2005)·2012
Same author

Cesarean section versus test of labor.

The New England journal of medicine·2010
Same author

BioJava: an open-source framework for bioinformatics.

Bioinformatics (Oxford, England)·2008
Same author

Renal outcome 25 years after donor nephrectomy.

The Journal of urology·2001
Same author

Clinical case-based approach to understanding intradialytic hypotension.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2001
Same author

Isolevuglandin-protein adducts in humans: products of free radical-induced lipid oxidation through the isoprostane pathway.

Biochimica et biophysica acta·2000
Same journal

Progressive Kidney Dysfunction and Ocular Clues: A Quiz.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2026
Same journal

Influence of Lactate Dehydrogenase on the Measurement of Blood Bicarbonate.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2026
Same journal

Urinary CXCL9 and CXCL10, Interstitial Inflammation and Disease Activity Over Time in Acute Interstitial Nephritis.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2026
Same journal

Hemophagocytic Lymphohistiocytosis and Fibroblast Growth Factor 23 (FGF23)-Induced Hypophosphatemia.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2026
Same journal

Kidney Transplantation Post-Chimeric Antigen Receptor T-Cell (CAR-T) Therapy in Multiple Myeloma.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2026
Same journal

Palliative Dialysis: Putting the Person First in Dialysis Care.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2026
See all related articles

Intradialytic hypotension (IDH) affects up to 50% of end-stage renal disease (ESRD) hemodialysis (HD) treatments. Managing IDH requires personalized HD prescriptions and pharmacologic interventions to prevent serious complications.

Area of Science:

  • Nephrology
  • Cardiovascular Medicine
  • Critical Care

Background:

  • Intradialytic hypotension (IDH) complicates 25-50% of end-stage renal disease (ESRD) hemodialysis (HD) treatments.
  • IDH presents with diverse symptoms and is linked to increased mortality risk in ESRD patients.
  • Recent research highlights hypotension's role in ESRD outcomes, contrasting with traditional hypertension focus.

Purpose of the Study:

  • To explore the pathophysiology of intradialytic hypotension (IDH) in ESRD patients undergoing hemodialysis (HD).
  • To review HD prescription modifications and pharmacologic strategies for preventing and treating IDH.
  • To emphasize identifying high-risk patients and customizing HD protocols.

Main Methods:

  • Review of current literature on IDH pathophysiology and management.

Related Experiment Videos

  • Discussion of technological and patient-dependent factors contributing to IDH.
  • Analysis of clinical case studies to illustrate management approaches.

    • Main Results:

    • IDH is associated with mechanisms including acute coronary syndrome, autoregulation dysfunction, ischemia, and arrhythmogenicity.
    • Endothelial dysfunction and altered myocardial vascular distribution contribute to vascular injury.
    • Personalized HD prescriptions and pharmacologic therapies are crucial for IDH management.

    Conclusions:

    • Effective IDH management necessitates identifying at-risk patients and tailoring HD prescriptions.
    • Pharmacologic interventions play a vital role in preventing and treating IDH events.
    • Continuous monitoring of chronic hypotension and IDH complications is essential in dialysis units.