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I(Ca(TTX)) channels are distinct from those generating the classical cardiac Na(+) current

Y Chen-Izu1, Q Sha, S R Shorofsky

  • 1Department of Medicine, School of Medicine, University of Maryland, Baltimore, Maryland 21201, USA.

Biophysical Journal
|October 19, 2001
PubMed
Summary

Calcium (Ca2+) is not required to demonstrate the tetrodotoxin-sensitive sodium (Na+) current component, I(Ca(TTX)). This study reveals two distinct sodium channel populations, not interconvertible, with differing calcium permeability.

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