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Aluminum Amides Derived from Metalation of N,N'-Bis(trimethylsilyl)ethylenediamine

Michael G. Gardiner1, George A. Koutsantonis, Stacey M. Lawrence

  • 1Department of Chemistry, Monash University, Clayton, Melbourne, Victoria, 3168, Australia, Department of Chemistry, University of Western Australia, Nedlands, Western Australia, 6009, Australia, and Faculty of Science and Technology, Griffith University, Nathan, Brisbane, Queensland, 4111, Australia.

Inorganic Chemistry
|September 11, 1996
PubMed

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Amide reduction requires two equivalents of the reducing agent, acting as a source of hydride ions. As shown in the figure, the reaction is initiated with a nucleophilic attack by the hydride ion at the carbonyl carbon to form a tetrahedral intermediate.
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