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Waiakeamide, a Cyclic Hexapeptide from the Sponge Ircinia dendroides(1)
Christina M. S. Mau1, Yoichi Nakao, Wesley Y. Yoshida
1Department of Zoology, The Natural History Museum, Cromwell Road, London SW7 5BD, U.K.
The Journal of Organic Chemistry
|September 6, 1996
Abstract:
From the sponge, Ircinia dendroides, collected in Indonesia we isolated a new cyclic hexapeptide, waiakeamide (1). Its structure, consisting of three proline residues, two methionine sulfoxides, and one thiazolylphenylalanine, was elucidated by spectral analysis and chemical degradation. Isolation and structural elucidation of waiakeamide is described.