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Updated: Oct 3, 2026

Preparation and Reactivity of a Triphosphenium Bromide Salt: A Convenient and Stable Source of Phosphorus(I)
08:46

Preparation and Reactivity of a Triphosphenium Bromide Salt: A Convenient and Stable Source of Phosphorus(I)

Published on: November 22, 2016

N-Phosphino- and N-Phosphonionitrilimines: From Nucleophilic to Electrophilic 1,3-Dipoles

Francisco Palacios1, Jaione Pagalday, Valérie Piquet

  • 1Departamento de Quimica Organica, Facultad de Farmacia, U.P.V./E.H.U., Apartado 450, 01080 Vitoria, Spain, and Laboratoire de Chimie de Coordination du CNRS, 205, route de Narbonne, 31077 Toulouse Cédex, France.

The Journal of Organic Chemistry
|January 24, 1997
PubMed

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Nitrous acid is a relatively weak and unstable acid prepared in situ by the reaction of sodium nitrite and cold, dilute hydrochloric acid. In an acidic solution, the nitrous acid undergoes protonation when it loses water to form a nitrosonium ion—an electrophile. Nitrous acid reacts with primary amines to give diazonium salts. The reaction is called diazotization of primary amines.
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